Cytoskeletal Architecture and Cell Morphogenesis

Our team explores how the cytoskeleton is organized, how it controls the establishment of functional membrane domains devoted to polarized cell growth or cell division, and how it is remodeled at mitotic entry for the assembly of the mitotic spindle and contractile ring, two complex molecular machines promoting chromosome segregation and cytokinesis. Most our studies are performed in the fission yeast where cell organization is stereotyped and the cytoskeleton relatively simple.