BORIS BARDOT

Professor,

Professor Université Paris Saclay

Recherche - Orsay

Spécialités / domaines

Development, cancer, genetics and epigenetics

Functions within Institut Curie:

Researcher Professor

Signaling and Neural Crest Development
Unit : Signaling, radiobiology and cancer (UMR3347 / U1021)

Présentation

Boris BARDOT is Professor at Paris-Saclay University. He teaches cell biology and the mechanisms of tumor transformation. His research projects focus on signaling pathways involved in development and cancers.

Publications

2020

Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance

Science Advances

Eléonore Toufektchan, Vincent Lejour, Romane Durand, Neelam Giri, Irena Draskovic, Boris Bardot, Pierre Laplante, Sara Jaber, Blanche P. Alter, José-Arturo Londono-Vallejo, Sharon A. Savage, Franck Toledo

(2020 10 Apr)

2017

Targeting MDM4 Splicing in Cancers

Genes

Boris Bardot, Franck Toledo

(2017 20 Feb)

2016

p53 downregulates the Fanconi anaemia DNA repair pathway

Nature Communications

Sara Jaber, Eléonore Toufektchan, Vincent Lejour, Boris Bardot, Franck Toledo

(2016 01 Apr)

2015

Mdm4: don't judge an isoform by its mRNA levels!

Aging

Boris Bardot, Franck Toledo

(2015 20 Oct)

2015

Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity

Oncogene

B Bardot, R Bouarich-Bourimi, J Leemput, V Lejour, A Hamon, L Plancke, A G Jochemsen, I Simeonova, M Fang, F Toledo

(2015 28 May)

2014

Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival

Oncogene

M Fang, I Simeonova, B Bardot, V Lejour, S Jaber, R Bouarich-Bourimi, A Morin, F Toledo

(2014 06 Mar)

2013

Mutant Mice Lacking the p53 C-Terminal Domain Model Telomere Syndromes

Cell Reports

Iva Simeonova, Sara Jaber, Irena Draskovic, Boris Bardot, Ming Fang, Rachida Bouarich-Bourimi, Vincent Lejour, Laure Charbonnier, Claire Soudais, Jean-Christophe Bourdon, Michel Huerre, Arturo Londono-Vallejo, Franck Toledo

(2013 01 Jun)

2013

Of mice and men

Transcription

Aurélie Morin, Boris Bardot, Iva Simeonova, Vincent Lejour, Rachida Bouarich-Bourimi, Franck Toledo

(2013 01 Mar)

2012

Fuzzy Tandem Repeats Containing p53 Response Elements May Define Species-Specific p53 Target Genes

PLOS Genetics

Iva Simeonova, Vincent Lejour, Boris Bardot, Rachida Bouarich-Bourimi, Aurélie Morin, Ming Fang, Laure Charbonnier, Franck Toledo

(2012 28 Jun)

2009

Three birds with one stone

Nature

Franck Toledo, Boris Bardot

(2009 01 Jul)