CHRISTINE VIARIS DE LESEGNO

mail

Doctor,

Ingénieur de recherche Inserm

Recherche - Paris

Spécialités / domaines

Cell biology,

Cellular and Tissue Imaging,

Microscopie optique,

Electronic microscopy

Functions within Institut Curie:

Chargé de mission d'enseignement

Membrane Mechanics and Dynamics of Intracellular Signaling
Unit : Cellular and Chemical Biology (UMR3666 / U1143)

Publications

2023

STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation

Nature Cell Biology

Natacha Zanin, Christine Viaris de Lesegno, Joanna Podkalicka, Thomas Meyer, Pamela Gonzalez Troncoso, Philippe Bun, Lydia Danglot, Daniela Chmiest, Sylvie Urbé, Jacob Piehler, Cédric M. Blouin, Christophe Lamaze

(2023 01 Mar)

2021

Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads

Frontiers in Immunology

Natacha Zanin, Christine Viaris de Lesegno, Christophe Lamaze, Cedric M. Blouin

(2021 20 Jan)

2020

Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation

Nature Communications

Lia Domingues, Ilse Hurbain, Floriane Gilles-Marsens, Julia Sirés-Campos, Nathalie André, Melissa Dewulf, Maryse Romao, Christine Viaris de Lesegno, Anne-Sophie Macé, Cédric Blouin, Christelle Guéré, Katell Vié, Graça Raposo, Christophe Lamaze, Cédric Delevoye

(2020 01 Dec)

2019

An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation

Nature Communications

Asier Echarri, Dácil M. Pavón, Sara Sánchez, María García-García, Enrique Calvo, Carla Huerta-López, Diana Velázquez-Carreras, Christine Viaris de Lesegno, Nicholas Ariotti, Ana Lázaro-Carrillo, Raffaele Strippoli, David De Sancho, Jorge Alegre-Cebollada, Christophe Lamaze, Robert G. Parton, Miguel A. Del Pozo

(2019 01 Dec)

2019

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells

Nature Communications

Melissa Dewulf, Darius Vasco Köster, Bidisha Sinha, Christine Viaris de Lesegno, Valérie Chambon, Anne Bigot, Mona Bensalah, Elisa Negroni, Nicolas Tardif, Joanna Podkalicka, Ludger Johannes, Pierre Nassoy, Gillian Butler-Browne, Christophe Lamaze, Cedric M. Blouin

(2019 01 Dec)

2018

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

Journal of Cell Biology

Stéphanie Torrino, Wei-Wei Shen, Cédric M. Blouin, Satish Kailasam Mani, Christine Viaris de Lesegno, Pierre Bost, Alexandre Grassart, Darius Köster, Cesar Augusto Valades-Cruz, Valérie Chambon, Ludger Johannes, Paolo Pierobon, Vassili Soumelis, Catherine Coirault, Stéphane Vassilopoulos, Christophe Lamaze

(2018 03 Dec)

2016

Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex

Nature Communications

Daniela Chmiest, Nanaocha Sharma, Natacha Zanin, Christine Viaris de Lesegno, Massiullah Shafaq-Zadah, Vonick Sibut, Florent Dingli, Philippe Hupé, Stephan Wilmes, Jacob Piehler, Damarys Loew, Ludger Johannes, Gideon Schreiber, Christophe Lamaze

(2016 01 Dec)

2016

Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation

Cell

Cédric M. Blouin, Yannick Hamon, Pauline Gonnord, Cédric Boularan, Jérémy Kagan, Christine Viaris de Lesegno, Richard Ruez, Sébastien Mailfert, Nicolas Bertaux, Damarys Loew, Christian Wunder, Ludger Johannes, Guillaume Vogt, Francesc-Xabier Contreras, Didier Marguet, Jean-Laurent Casanova, Céline Galès, Hai-Tao He, Christophe Lamaze

(2016 01 Aug)