DANIELE FACHINETTI

Doctor,

Research Director CNRS

Recherche - Paris

Spécialités / domaines

Cell biology,

Molecular biology,

Genetics

Functions within Institut Curie:

Team Leader
Molecular Mechanisms of Chromosome Dynamics
Unité : Cell Biology and Cancer (UMR144)

Présentation

Team leader of the "Molecular Mechanisms of Chromosome Dynamics" group

Publications

2022

Kronos scRT: a uniform framework for single-cell replication timing analysis

Nature Communications

2022

CENP-B-mediated DNA loops regulate activity and stability of human centromeres

Molecular Cell

Florian Chardon, Aleksandre Japaridze, Hannes Witt, Leonid Velikovsky, Camellia Chakraborty, Therese Wilhelm, Marie Dumont, Wayne Yang, Carlos Kikuti, Stephane Gangnard, Anne-Sophie Mace, Gijs Wuite, Cees Dekker, Daniele Fachinetti

(2022 01 May)

2021

CENP-A overexpression promotes distinct fates in human cells, depending on p53 status

Communications Biology

Daniel Jeffery, Alberto Gatto, Katrina Podsypanina, Charlène Renaud-Pageot, Rebeca Ponce Landete, Lorraine Bonneville, Marie Dumont, Daniele Fachinetti, Geneviève Almouzni

(2021 01 Dec)

2021

Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A K124ub

Cell Reports

2021

Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

Developmental Cell

Marica Rosaria Ippolito, Valentino Martis, Sara Martin, Andréa E. Tijhuis, Christy Hong, René Wardenaar, Marie Dumont, Johanna Zerbib, Diana C.J. Spierings, Daniele Fachinetti, Uri Ben-David, Floris Foijer, Stefano Santaguida

(2021 01 Sep)

2021

Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics

bioRxiv

Veer I. P. Keizer, Simon Grosse-Holz, Maxime Woringer, Laura Zambon, Koceila Aizel, Maud Bongaerts, Lorena Kolar-Znika, Vittore F. Scolari, Sebastian Hoffmann, Edward J. Banigan, Leonid A. Mirny, Maxime Dahan, Daniele Fachinetti, Antoine Coulon

(2021 21 Apr)

2021

CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity

Journal of Cell Biology

Roshan L. Shrestha, Austin Rossi, Darawalee Wangsa, Ann K. Hogan, Kimberly S. Zaldana, Evelyn Suva, Yang Jo Chung, Chelsea L. Sanders, Simone Difilippantonio, Tatiana S. Karpova, Baktiar Karim, Daniel R. Foltz, Daniele Fachinetti, Peter D. Aplan, Thomas Ried, Munira A. Basrai

(2021 05 Apr)

2021

CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

Proceedings of the National Academy of Sciences

Simona Giunta, Solène Hervé, Ryan R. White, Therese Wilhelm, Marie Dumont, Andrea Scelfo, Riccardo Gamba, Cheng Kit Wong, Giulia Rancati, Agata Smogorzewska, Hironori Funabiki, Daniele Fachinetti

(2021 09 Mar)

2021

Induction of spontaneous human neocentromere formation and long-term maturation

Journal of Cell Biology

Marina Murillo-Pineda, Luis P. Valente, Marie Dumont, João F. Mata, Daniele Fachinetti, Lars E.T. Jansen

(2021 01 Mar)

2020

Artificial chromosomes

Experimental Cell Research

Daniele Fachinetti, Hiroshi Masumoto, Natalay Kouprina

(2020 01 Nov)