DEBORAH BOURC'HIS

Doctor,

Research Director Inserm

Recherche - Paris

Spécialités / domaines

Development, cancer, genetics and epigenetics

Functions within Institut Curie:

Team Leader

Epigenetic Decisions and Reproduction in Mammals
Unit : Genetics and Developmental Biology (UMR3215 / U934)

Publications

2022

The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates

eLife

Juliane Glaser, Julian Iranzo, Maud Borensztein, Mattia Marinucci, Angelica Gualtieri, Colin Jouhanneau, Aurélie Teissandier, Carles Gaston-Massuet, Deborah Bourc'his

(2022 20 Jan)

2019

Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency

eLife

Maxim Greenberg, Aurélie Teissandier, Marius Walter, Daan Noordermeer, Deborah Bourc'his

(2019 16 Apr)

2017

Gene body DNA methylation conspires with H3K36me3 to preclude aberrant transcription

The EMBO Journal

Aurélie Teissandier, Déborah Bourc'his

(2017 01 Jun)

2017

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression

Journal of Cell Science

Yara Tarabay, Mayada Achour, Marius Teletin, Tao Ye, Aurélie Teissandier, Manuel Mark, Déborah Bourc'his, Stéphane Viville

(2017 15 Apr)

2017

Transient transcription in the early embryo sets an epigenetic state that programs postnatal growth

Nature Genetics

Maxim V C Greenberg, Juliane Glaser, Máté Borsos, Fatima El Marjou, Marius Walter, Aurélie Teissandier, Déborah Bourc'his

(2017 01 Jan)

2016

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

eLife

Marius Walter, Aurélie Teissandier, Raquel Pérez-Palacios, Déborah Bourc'his

(2016 27 Jan)

2015

Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency

REPRODUCTION

Hung-Fu Liao, Chu-Fan Mo, Shinn-Chih Wu, Dai-Han Cheng, Chih-Yun Yu, Kai-Wei Chang, Tzu-Hao Kao, Chia-Wei Lu, Marina Pinskaya, Antonin Morillon, Shih-Shun Lin, Winston T K Cheng, Déborah Bourc'his, Timothy Bestor, Li-Ying Sung, Shau-Ping Lin

(2015 01 Oct)

2015

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

Genes & Development

Natasha Zamudio, Joan Barau, Aurélie Teissandier, Marius Walter, Maté Borsos, Nicolas Servant, Déborah Bourc'his

(2015 15 Jun)

2015

Germline correction of an epimutation related to Silver-Russell syndrome

Human Molecular Genetics

C. Bruno, V. Carmignac, I. Netchine, C. Choux, Y. Duffourd, L. Faivre, C. Thauvin-Robinet, Y. Le Bouc, P. Sagot, D. Bourc'his, P. Fauque

(2015 15 Jun)

2014

The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals

Genes & Development

Rachel Duffié, Sophie Ajjan, Maxim V. Greenberg, Natasha Zamudio, Martin Escamilla del Arenal, Julian Iranzo, Ikuhiro Okamoto, Sandrine Barbaux, Patricia Fauque, Déborah Bourc'his

(2014 01 Mar)

Actualites

Congratulations to Déborah Bourc’his, winner of an ERC Advanced Grant

Understanding the role of epigenetics in male fertility