Research Director CNRS
Recherche - Paris
Spécialités / domaines
Recombinant antibodies,
Cell biology,
Cellular and Tissue Imaging,
Multi-scale physics-chemistry-biology and cancer (molecules, cells, tissues and organisms)
Functions within Institut Curie:

Franck Perez is Research Director at CNRS and Chairman of the "Cell Biology and Cancer" Unit of the Institut Curie in Paris. His group is studying intracellular trafficking with an important focus on the development of new methods and tools for Cell Biology studies. For example, he developed at the Institut Curie the use of automated cellular screening and co-founded a High Content screening platform (BioPhenics, with Dr. J. Camonis) directed by Elaine del Nery. In addition, his group created a novel trafficking assay and have strongly invested on the development of recombinant antibodies for cell biology. Notably, with Sandrine Moutel he developed a novel antibody library based on a humanized nanobody scaffold and created a therapeutic antibody platform.

Prior to being recruited by CNRS, F. Perez was Maître-Assistant at the University of Geneva in Switzerland, in the laboratory of Prof. T. E Kreis (1996-1999) where he worked on microtubule dynamics and intracellular trafficking. F. Perez received his PhD. in 1996 for his work in the laboratory of A. Prochiantz at the Ecole Normale Supérieure (Paris, France) on the regulation of neuroendocrine secretion and on the development of cell internalization peptides. Before his PhD., F. Perez graduated in Cell biology and Genetics at the University Paris VII.

F. Perez is an EMBO member, author of more than a hundred articles and over ten patents, and is the co-founder of three biotech companies including Honing Biosciences, spin-off from the Institut Curie which develops next generation cell-based therapies

Integrated High-Throughput Screening and Large-Scale Isobolographic Analysis to Accelerate the Discovery of Radiosensitizers With Greater Selectivity for Cancer Cells
International Journal of Radiation Oncology*Biology*Physics
Pierre Verrelle, Pierre Gestraud, Florent Poyer, Adèle Soria, Sarah Tessier, Aurianne Lescure, Elodie Anthony, Maxime Corbé, Sophie Heinrich, Claire Beauvineau, Ludovic Chaput, Anton Granzhan, Sandrine Piguel, Franck Perez, Marie-Paule Teulade-Fichou, Frédérique Megnin-Chanet, Elaine Del Nery
Golgi maturation‐dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3
The EMBO Journal
Riccardo Rizzo, Domenico Russo, Kazuo Kurokawa, Pranoy Sahu, Bernadette Lombardi, Domenico Supino, Mikhail A Zhukovsky, Anthony Vocat, Prathyush Pothukuchi, Vidya Kunnathully, Laura Capolupo, Gaelle Boncompain, Carlo Vitagliano, Federica Zito Marino, Gabriella Aquino, Daniela Montariello, Petra Henklein, Luigi Mandrich, Gerardo Botti, Henrik Clausen, Ulla Mandel, Toshiyuki Yamaji, Kentaro Hanada, Alfredo Budillon, Franck Perez, Seetharaman Parashuraman, Yusuf A Hannun, Akihiko Nakano, Daniela Corda, Giovanni D’Angelo, Alberto Luini
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
British Journal of Cancer
Maud Kamal, , Sonia Lameiras, Marc Deloger, Adeline Morel, Sophie Vacher, Charlotte Lecerf, Célia Dupain, Emmanuelle Jeannot, Elodie Girard, Sylvain Baulande, Coraline Dubot, Gemma Kenter, Ekaterina S. Jordanova, Els M. J. J. Berns, Guillaume Bataillon, Marina Popovic, Roman Rouzier, Wulfran Cacheux, Christophe Le Tourneau, Alain Nicolas, Nicolas Servant, Suzy M. Scholl, Ivan Bièche
High seroprevalence but short‐lived immune response to SARS‐CoV‐2 infection in Paris
European Journal of Immunology
François Anna, Sophie Goyard, Ana Ines Lalanne, Fabien Nevo, Marion Gransagne, Philippe Souque, Delphine Louis, Véronique Gillon, Isabelle Turbiez, François‐Clément Bidard, Aline Gobillion, Alexia Savignoni, Maude Guillot‐Delost, François Dejardin, Evelyne Dufour, Stéphane Petres, Odile Richard‐Le Goff, Zaineb Choucha, Olivier Helynck, Yves L. Janin, Nicolas Escriou, Pierre Charneau, Franck Perez, Thierry Rose, Olivier Lantz