KARINE LAUD-DUVAL

mail

Doctor

Recherche - Paris

Spécialités / domaines

Cell biology,

CRISPR,

Cancer,

Single Cell

Functions within Institut Curie:

Research Engineer

Diversity and Plasticity of Chilhood Tumors (DePiCT)
Unit : Cancer, Heterogeneity, Instability and Plasticity - CHIP (U830)

Présentation

Ingénieur de recherche INSERM U830 Cancer, Héterogeneïté, Instabilité et Plasticité

Doctorat in Biology of 'Université Pierre et Mari-Curie- Paris and post-doc position in Institut Gustave Roussy " Genetic predisposition in melanoma"

Research in Institut Curie:

Study of Ewing pediatric tumeur by the identification of new therapeutic targets and characterization of expression heterogeneity of oncogene driver of this cancer.

Interaction with " département physico-chimique" de l'institut Curie

Publications

2022

Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions

Molecular Cell

Julien Vibert, Olivier Saulnier, Céline Collin, Floriane Petit, Kyra J.E. Borgman, Jérômine Vigneau, Maud Gautier, Sakina Zaidi, Gaëlle Pierron, Sarah Watson, Nadège Gruel, Clémence Hénon, Sophie Postel-Vinay, Marc Deloger, Virginie Raynal, Sylvain Baulande, Karine Laud-Duval, Véronique Hill, Sandrine Grossetête, Florent Dingli, Damarys Loew, Jacob Torrejon, Olivier Ayrault, Martin F. Orth, Thomas G.P. Grünewald, Didier Surdez, Antoine Coulon, Joshua J. Waterfall, Olivier Delattre

(2022 01 Jul)

2022

Upregulation of the Mevalonate Pathway through EWSR1-FLI1/EGR2 Regulatory Axis Confers Ewing Cells Exquisite Sensitivity to Statins

Cancers

Charlie Buchou, Karine Laud-Duval, Wietske van der Ent, Sandrine Grossetête, Sakina Zaidi, Géraldine Gentric, Maxime Corbé, Kévin Müller, Elaine Del Nery, Didier Surdez, Olivier Delattre

(2022 08 May)

2021

STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

Cancer Cell

Didier Surdez, Sakina Zaidi, Sandrine Grossetête, Karine Laud-Duval, Anna Sole Ferre, Lieke Mous, Thomas Vourc'h, Franck Tirode, Gaelle Pierron, Virginie Raynal, Sylvain Baulande, Erika Brunet, Véronique Hill, Olivier Delattre

(2021 01 Jun)

2021

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

Nucleic Acids Research

Olivier Saulnier, Katia Guedri-Idjouadiene, Marie-Ming Aynaud, Alina Chakraborty, Jonathan Bruyr, Joséphine Pineau, Tina O’Grady, Olivier Mirabeau, Sandrine Grossetête, Bartimée Galvan, Margaux Claes, Zahra Al Oula Hassoun, Benjamin Sadacca, Karine Laud, Sakina Zaïdi, Didier Surdez, Sylvain Baulande, Xavier Rambout, Franck Tirode, Martin Dutertre, Olivier Delattre, Franck Dequiedt

(2021 21 May)

2017

Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells

Oncogene

G-A Franzetti, K Laud-Duval, W van der Ent, A Brisac, M Irondelle, S Aubert, U Dirksen, C Bouvier, G de Pinieux, E Snaar-Jagalska, P Chavrier, O Delattre

(2017 01 Jun)

2013

Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis

Nucleic Acids Research

Gautier Stoll, Didier Surdez, Franck Tirode, Karine Laud, Emmanuel Barillot, Andrei Zinovyev, Olivier Delattre

(2013 01 Oct)

2013

MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor

Oncogene

G-A Franzetti, K Laud-Duval, D Bellanger, M-H Stern, X Sastre-Garau, O Delattre

(2013 15 Aug)

2012