MARIA LUISA MARTIN FARALDO

Doctor,

Chargé de recherche

Recherche - Paris

Spécialités / domaines

Cell biology,

Developmental biology,

Cancer

Functions within Institut Curie:

Permanent Researcher

Fate and plasticity of epithelial stem cells
Unit : Genetics and Developmental Biology (UMR3215 / U934)

Présentation

I am a Chargé de Recherche in Silvia Fre's team. I am interested in the mechanisms that control the regulation of mammary stem cells and their role in normal and tumor development of the mammary gland. My current projects focus, in particular, on integrins and the Wnt/beta-catenin signaling pathway.

Publications

2024

Alpha-6 integrin deletion delays the formation of Brca1/p53-deficient basal-like breast tumors by restricting luminal progenitor cell expansion

Breast Cancer Research

Marisa M. Faraldo, Mathilde Romagnoli, Loane Wallon, Pierre Dubus, Marie-Ange Deugnier, Silvia Fre

(2024 04 Jun)

2024

Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland

The EMBO Journal

Claudia Carabaña, Wenjie Sun, Camila Veludo Ramos, Mathilde Huyghe, Meghan Perkins, Aurélien Maillot, Robin Journot, Fatima Hartani, Marisa M Faraldo, Bethan Lloyd-Lewis, Silvia Fre

(2024 17 May)

2022

Luminal progenitors undergo partial epithelial-to-mesenchymal transition at the onset of basal-like breast tumorigenesis

bioRxiv

2021

In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation

bioRxiv

Bethan Lloyd-Lewis, Francesca Gobbo, Meghan Perkins, Guillaume Jacquemin, Marisa M Faraldo, Silvia Fre

(2021 22 Jun)