MARIE-PAULE TEULADE-FICHOU

Doctor

Recherche - Orsay

Spécialités / domaines

Biologie et chimie des radiations, signalisation cellulaire et cancer

Functions within Institut Curie:

Team Leader

Drugs and probes for Nucleic acids secondary structures
Unit : Chemistry and Modelling for Biology of Cancer (UMR9187 / U1196)

Publications

2024

A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome

Journal of Biomedical Science

Keli Kuang, Chunyan Li, Fatlinda Maksut, Deepanjan Ghosh, Robin Vinck, Maolin Wang, Joël Poupon, Run Xiang, Wen Li, Fei Li, Zhu Wang, Junrong Du, Marie-Paule Teulade-Fichou, Gilles Gasser, Sophie Bombard, Tao Jia

(2024 13 May)

2024

Systematic evaluation of benchmark G4 probes and G4 clinical drugs using three biophysical methods: A guideline to evaluate rapidly G4‐binding affinity.

ChemBioChem

Eugenie Laigre, Hugues Bonnet, Claire Beauvineau, Thomas Lavergne, Daniela Verga, Eric Defrancq, Jerome Dejeu, Marie-Paule Teulade-Fichou

(2024 15 Apr)

2024

Integrated High-Throughput Screening and Large-Scale Isobolographic Analysis to Accelerate the Discovery of Radiosensitizers With Greater Selectivity for Cancer Cells

International Journal of Radiation Oncology*Biology*Physics

Pierre Verrelle, Pierre Gestraud, Florent Poyer, Adèle Soria, Sarah Tessier, Aurianne Lescure, Elodie Anthony, Maxime Corbé, Sophie Heinrich, Claire Beauvineau, Ludovic Chaput, Anton Granzhan, Sandrine Piguel, Franck Perez, Marie-Paule Teulade-Fichou, Frédérique Megnin-Chanet, Elaine Del Nery

(2024 01 Apr)

2023

Alternative splicing of <i>BCL-x</i> is controlled by RBM25 binding to a G-quadruplex in <i>BCL-x</i> pre-mRNA

Nucleic Acids Research

Ronan Le Sénéchal, Marc Keruzoré, Alicia Quillévéré, Nadège Loaëc, Van-Trang Dinh, Oksana Reznichenko, Pedro Guixens-Gallardo, Laurent Corcos, Marie-Paule Teulade-Fichou, Anton Granzhan, Marc Blondel

(2023 09 Oct)

2022

Type I arginine methyltransferases are intervention points to unveil the oncogenic Epstein-Barr virus to the immune system

Nucleic Acids Research

Gaelle Angrand, Alicia Quillévéré, Nadège Loaëc, Van-Trang Dinh, Ronan Le Sénéchal, Rahima Chennoufi, Patricia Duchambon, Marc Keruzoré, Rodrigo Prado Martins, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Marc Blondel

(2022 11 Nov)

2022

Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces

Antimicrobial Agents and Chemotherapy

Delphine Lapaillerie, Cathy Charlier, Véronique Guyonnet-Dupérat, Emilie Murigneux, Henrique S. Fernandes, Fábio G. Martins, Rita P. Magalhães, Tatiana F. Vieira, Clémence Richetta, Frédéric Subra, Samuel Lebourgeois, Charlotte Charpentier, Diane Descamps, Benoît Visseaux, Pierre Weigel, Alexandre Favereaux, Claire Beauvineau, Frédéric Buron, Marie-Paule Teulade-Fichou, Sylvain Routier, Sarah Gallois-Montbrun, Laurent Meertens, Olivier Delelis, Sérgio F. Sousa, Vincent Parissi

(2022 16 Aug)

2022

The different activities of RNA G-quadruplex structures are controlled by flanking sequences

Life Science Alliance

Alice J-L Zheng, Aikaterini Thermou, Pedro Guixens Gallardo, Laurence Malbert-Colas, Chrysoula Daskalogianni, Nathan Vaudiau, Petter Brohagen, Anton Granzhan, Marc Blondel, Marie-Paule Teulade-Fichou, Rodrigo Prado Martins, Robin Fahraeus

(2022 01 Feb)

2021

BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells

Nucleic Acids Research

Thibaut Masson, Corinne Landras Guetta, Eugénie Laigre, Anne Cucchiarini, Patricia Duchambon, Marie-Paule Teulade-Fichou, Daniela Verga

(2021 16 Dec)

2021

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

Nucleic Acids Research

Marc Lavigne, Olivier Helynck, Pascal Rigolet, Rofia Boudria-Souilah, Mireille Nowakowski, Bruno Baron, Sébastien Brülé, Sylviane Hoos, Bertrand Raynal, Lionel Guittat, Claire Beauvineau, Stéphane Petres, Anton Granzhan, Jean Guillon, Geneviève Pratviel, Marie-Paule Teulade-Fichou, Patrick England, Jean-Louis Mergny, Hélène Munier-Lehmann

(2021 21 Jul)

2021

Pt-ttpy, a G-quadruplex binding platinum complex, induces telomere dysfunction and G-rich regions DNA damage

Metallomics

Samar Ali, Emilia Puig Lombardi, Deepanjan Ghosh, Tao Jia, Géraldine Vitry, Lina Saker, Joël Poupon, Marie-Paule Teulade-Fichou, Alain Nicolas, Arturo Londono-Vallejo, Sophie Bombard

(2021 12 Jun)