MAXIME DUBAIL

Université Paris Saclay

Recherche - Orsay

Spécialités / domaines

Biologie et chimie des radiations, signalisation cellulaire et cancer,

Single Cell

Functions within Institut Curie:

PhD Student

DNA Repair, Radiations and Innovative Cancer Therapies
Unit : Signaling, radiobiology and cancer (UMR3347 / U1021)

Présentation

I am a PhD student in the team Repair, Radiation and Innovative Cancer Therapies. My project consists in identifying molecular biomarkers and cellular targets to predict the response of healthy lung tissue to different irradiation protocols including FLASH radiotherapy. During my M2 internship in the team and during a fixed-term contract, I also worked on the development of new ex vivo models of organotypic lung slices to study the response of healthy tissue in the short term after irradiation.

Publications

2024

The AsiDNA™ decoy mimicking DSBs protects the normal tissue from radiation toxicity through a DNA-PK/p53/p21-dependent G1/S arrest

NAR Cancer

Anouk Sesink, Margaux Becerra, Jia-Ling Ruan, Sophie Leboucher, Maxime Dubail, Sophie Heinrich, Wael Jdey, Kristoffer Petersson, Charles Fouillade, Nathalie Berthault, Marie Dutreix, Pierre-Marie Girard

(2024 09 Jan)

2023

Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

Cells

Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade

(2023 11 Oct)

2023

Lipid Polyunsaturated Fatty Acid Chains in Mouse Kidneys Were Increased within 5 min of a Single High Dose Whole Body Irradiation

International Journal of Molecular Sciences

Wenxin Li, Chi Zhang, Shuhei Aramaki, Lili Xu, Shogo Tsuge, Takumi Sakamoto, Md. Al Mamun, Ariful Islam, Takamitsu Hayakawa, Yusuke Takanashi, Maxime Dubail, Kenta Konishi, Tomohito Sato, Tomoaki Kahyo, Charles Fouillade, Katsumasa Nakamura, Mitsutoshi Setou

(2023 04 Aug)