default_medecin

NADEGE GRUEL

Doctor
Recherche - Paris
Spécialités / domaines
Anticorps recombinants,
Biologie intégrative des tumeurs, immunologie et environnement,
Biologie moléculaire,
Cancer,
Génomique,
Single Cell,
Séquençage
Functions within Institut Curie:
  • Research engineer
    Diversity and Plasticity of Chilhood Tumors (DePiCT)
    Unit : Cancer, Heterogeneity, Instability and Plasticity - CHIP (U830)
Présentation

With a double specialization, (immunology, master 2 and genetics, master 2 + PhD), I have always worked in laboratories at the research-clinical interface (antibody biotechnology, molecular characterization of breast cancer, intratumoral heterogeneity of sarcomas), often in pairs with doctors from the institute. These different missions showed my adaptability and the extent of my theoretical knowledge (from immunology to genetics) and techniques (analysis on single cells).

Publications
CXCR6 deficiency impairs cancer vaccine efficacy and CD8+ resident memory T-cell recruitment in head and neck and lung tumors
Journal for ImmunoTherapy of Cancer
Soumaya Karaki, Charlotte Blanc, Thi Tran, Isabelle Galy-Fauroux, Alice Mougel, Estelle Dransart, Marie Anson, Corinne Tanchot, Lea Paolini, Nadege Gruel, Laure Gibault, Francoise Lepimpec-Barhes, Elizabeth Fabre, Nadine Benhamouda, Cecile Badoual, Diane Damotte, Emmanuel Donnadieu, Sebastian Kobold, Fathia Mami-Chouaib, Rachel Golub, Ludger Johannes, Eric Tartour
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution
Cell Reports
Marie-Ming Aynaud, Olivier Mirabeau, Nadege Gruel, Sandrine Grossetête, Valentina Boeva, Simon Durand, Didier Surdez, Olivier Saulnier, Sakina Zaïdi, Svetlana Gribkova, Aziz Fouché, Ulykbek Kairov, Virginie Raynal, Franck Tirode, Thomas G.P. Grünewald, Mylene Bohec, Sylvain Baulande, Isabelle Janoueix-Lerosey, Jean-Philippe Vert, Emmanuel Barillot, Olivier Delattre, Andrei Zinovyev
Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression
The American Journal of Pathology
Pierre Romero, Vanessa Benhamo, Gabrielle Deniziaut, Laetitia Fuhrmann, Frédérique Berger, Elodie Manié, Jaydutt Bhalshankar, Sophie Vacher, Cécile Laurent, Elisabetta Marangoni, Nadège Gruel, Gaëtan MacGrogan, Roman Rouzier, Olivier Delattre, Tatiana Popova, Fabien Reyal, Marc-Henri Stern, Dominique Stoppa-Lyonnet, Caterina Marchiò, Ivan Bièche, Anne Vincent-Salomon
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis
Genes & Development
Michel Wassef, Veronica Rodilla, Aurélie Teissandier, Bruno Zeitouni, Nadege Gruel, Benjamin Sadacca, Marie Irondelle, Margaux Charruel, Bertrand Ducos, Audrey Michaud, Matthieu Caron, Elisabetta Marangoni, Philippe Chavrier, Christophe Le Tourneau, Maud Kamal, Eric Pasmant, Michel Vidaud, Nicolas Servant, Fabien Reyal, Dider Meseure, Anne Vincent-Salomon, Silvia Fre, Raphaël Margueron