SIMON GEMBLE

mail

Doctor,

Chargé de recherche

Recherche - Paris

Spécialités / domaines

Cell biology,

Cancer,

Genome integrity

Functions within Institut Curie:

Permanent Researcher

Biology of centrosomes and genetic instability
Unit : Cell Biology and Cancer (UMR144)

Publications

2023

Experimental Approaches to Generate and Isolate Human Tetraploid Cells

Methods in Molecular Biology

Sara Vanessa Bernhard, Simon Gemble, Renata Basto, Zuzana Storchova

(2023 01 Jan)

2022

Genetic instability from a single S phase after whole-genome duplication

Nature

Simon Gemble, René Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E. Tijhuis, Sara Vanessa Bernhard, Diana C. J. Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto

(2022 07 Apr)

2021

Identification and Analysis of Different Types of UFBs

Homologous Recombination

Simon Gemble, Mounira Amor-Guéret

(2021 01 Jan)

2020

A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD+

Scientific Reports

Sandra Cunha Silveira, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Simon Gemble, Elias Bou Samra, Hamza Mameri, Patricia Duchambon, Christelle Machon, Jérôme Guitton, Mounira Amor-Guéret

(2020 01 Dec)

2020

CHRONOCRISIS: When Cell Cycle Asynchrony Generates DNA Damage in Polyploid Cells

BioEssays

Simon Gemble, Renata Basto

(2020 01 Oct)

2020

Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms

Open Biology

Simon Gemble, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Gaëlle Fontaine, Sarah Lambert, Mounira Amor-Guéret

(2020 01 May)

2020

Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells

Journal of Cell Biology

Alix Goupil, Maddalena Nano, Gaëlle Letort, Simon Gemble, Frances Edwards, Oumou Goundiam, Delphine Gogendeau, Carole Pennetier, Renata Basto

(2020 06 Apr)

2019

Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells

Current Biology

Maddalena Nano, Simon Gemble, Anthony Simon, Carole Pennetier, Vincent Fraisier, Veronique Marthiens, Renata Basto

(2019 01 Nov)

2019

Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity

Current Biology

Simon Gemble, Anthony Simon, Carole Pennetier, Marie Dumont, Solène Hervé, Franz Meitinger, Karen Oegema, Raphaël Rodriguez, Geneviève Almouzni, Daniele Fachinetti, Renata Basto

(2019 01 Sep)

2018

E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding

PLOS ONE

Jennifer Allègre, Jessy Cartier, Valérie Glorian, Nathalie Droin, Baptiste Dumetier, Cémile Kayaci, Jean Berthelet, Simon Gemble, Céline Vuillier, Laurent Maillet, Carmen Garrido, Laurence Dubrez

(2018 25 Oct)