SOPHIE BOMBARD

Doctor

Recherche - Orsay

Spécialités / domaines

Biologie et chimie des radiations, signalisation cellulaire et cancer

Functions within Institut Curie:

Permanent researcher

Drugs and probes for Nucleic acids secondary structures
Unit : Chemistry and Modelling for Biology of Cancer (UMR9187 / U1196)

Publications

2022

Photoactivatable V‐Shaped Bifunctional Quinone Methide Precursors as a New Class of Selective G‐quadruplex Alkylating Agents

Chemistry – A European Journal

Alberto Lena, Alessandra Benassi, Michele Stasi, Christine Saint-Pierre, Mauro Freccero, Didier Gasparutto, Sophie Bombard, Filippo Doria, Daniela Verga

(2022 21 Jun)

2022

Acridine–O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity

European Journal of Medicinal Chemistry

Jaime Franco Pinto, Alexandra Fillion, Patricia Duchambon, Sophie Bombard, Anton Granzhan

(2022 01 Jan)

2021

Photoactivatable Small‐Molecule Inhibitors for Light‐Controlled TAM Kinase Activity

ChemPhotoChem

Julie Le Bescont, Liliane Mouawad, Thomas Boddaert, Sophie Bombard, Sandrine Piguel

(2021 01 Nov)

2021

Pt-ttpy, a G-quadruplex binding platinum complex, induces telomere dysfunction and G-rich regions DNA damage

Metallomics

Samar Ali, Emilia Puig Lombardi, Deepanjan Ghosh, Tao Jia, Géraldine Vitry, Lina Saker, Joël Poupon, Marie-Paule Teulade-Fichou, Alain Nicolas, Arturo Londono-Vallejo, Sophie Bombard

(2021 12 Jun)

2020

Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes

Biochemistry

Abhijit Saha, Patricia Duchambon, Vanessa Masson, Damarys Loew, Sophie Bombard, Marie-Paule Teulade-Fichou

(2020 31 Mar)

2019

Interaction of Functionalized Naphthalenophanes with Abasic Sites in DNA: DNA Cleavage, DNA Cleavage Inhibition, and Formation of Ligand–DNA Adducts

Chemistry – A European Journal

Coralie Caron, Xuan N. T. Duong, Régis Guillot, Sophie Bombard, Anton Granzhan

(2019 06 Feb)

2019

Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA

Molecules

Elodie Morel, Claire Beauvineau, Delphine Naud-Martin, Corinne Landras-Guetta, Daniela Verga, Deepanjan Ghosh, Sylvain Achelle, Florence Mahuteau-Betzer, Sophie Bombard, Marie-Paule Teulade-Fichou

(2019 23 Jan)

2019

Probing ligand and cation binding sites in G-quadruplex nucleic acids by mass spectrometry and electron photodetachment dissociation sequencing

The Analyst

Dababrata Paul, Adrien Marchand, Daniela Verga, Marie-Paule Teulade-Fichou, Sophie Bombard, Frédéric Rosu, Valérie Gabelica

(2019 01 Jan)

2018

Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in BrU-Substituted DNA

Scientific Reports

Abhijit Saha, Sophie Bombard, Anton Granzhan, Marie-Paule Teulade-Fichou

(2018 01 Dec)

2018

Platinum Complexes Can Bind to Telomeres by Coordination

International Journal of Molecular Sciences

Lina Saker, Samar Ali, Caroline Masserot, Guillaume Kellermann, Joel Poupon, Marie-Paule Teulade-Fichou, Evelyne Ségal-Bendirdjian, Sophie Bombard

(2018 03 Jul)