STEPHAN VAGNER

Doctor,

Research Director Inserm

Recherche - Orsay

Spécialités / domaines

RNA,

Cancer

Functions within Institut Curie:

Research Unit Director

Genome Integrity, RNA and Cancer (UMR3348)
Team Leader

RNA Biology, Signalling and Cancer (U1278)
Unit : Genome Integrity, RNA and Cancer (UMR3348)
Coordinateur de site

Direction du Centre de Recherche

Présentation

1995: PhD in Molecular Biology, Université Toulouse III

1995-1997: Post-doc at the EMBL, Heidelberg

1998-1999: Staff scientist (CR Inserm) at Inserm, Toulouse

2000-2004: Group Leader Institut Louis Bugnard/Inserm U589, Toulouse

2005-2010: Group Leader Institut Claudius Regaud/Inserm U563, Toulouse

2011-2012: Gustave Roussy, Inserm U981, Villejuif

Since 2013: Group Leader Institut Curie/CNRS UMR3348, Orsay

2015-2019: Deputy Director CNRS UMR3348, Orsay

Since 2018: Professor Ecole Polytechnique, Palaiseau

Since 2020: Director CNRS UMR3348 / INSERM U1278, Orsay

Publications

2023

Post-transcriptional checkpoints in autoimmunity

Nature Reviews Rheumatology

Rami Bechara, Stephan Vagner, Xavier Mariette

(2023 13 Jun)

2023

Post‐transcriptional polyadenylation site cleavage maintains 3′‐end processing upon DNA damage

The EMBO Journal

Rym Sfaxi, Biswendu Biswas, Galina Boldina, Mandy Cadix, Nicolas Servant, Huimin Chen, Daniel R Larson, Martin Dutertre, Caroline Robert, Stéphan Vagner

(2023 03 Apr)

2022

The multiple roles of LDH in cancer

Nature Reviews Clinical Oncology

Giuseppina Claps, Sara Faouzi, Virginie Quidville, Feras Chehade, Shensi Shen, Stéphan Vagner, Caroline Robert

(2022 01 Dec)

2022

Using genetics to predict toxicity of cancer immunotherapy

Nature Medicine

Caroline Robert, Stéphan Vagner, Xavier Mariette

(2022 01 Dec)

2022

Compartment-specific and ELAVL1-coordinated regulation of intronic polyadenylation isoforms by doxorubicin

Genome Research

Alina Chakraborty, Mandy Cadix, Sébastien Relier, Nicolò Taricco, Tina Alaeitabar, Alexandre Devaux, Céline M. Labbé, Sylvain Martineau, Amélie Heneman-Masurel, Pierre Gestraud, Alberto Inga, Nicolas Servant, Stéphan Vagner, Martin Dutertre

(2022 01 Jul)

2022

At the crossroads of RNA biology, genome integrity and cancer

Bulletin du Cancer

Biswendu Biswas, Rady Chaaban, Shrena Chakraborty, Alexandre Devaux, Ana Luisa Dian, Anna Minello, Jenny Kaur Singh, Stephan Vagner, Patricia Uguen, Sarah Lambert, Martin Dutertre, Aura Carreira

(2022 01 Jun)

2022

Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells

Cancers

Raquel Vivet-Noguer, Malcy Tarin, Christine Canbezdi, Stephane Dayot, Lisseth Silva, Alexandre Houy, Sylvain Martineau, Virginie Mieulet, Géraldine Gentric, Damarys Loew, Bérangère Lombard, Fariba Nemati, Sophie Richon, Lea Guyonnet, Vincent Servois, Stephan Vagner, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi

(2022 24 Apr)

2022

Differential Effects on the Translation of Immune-Related Alternatively Polyadenylated mRNAs in Melanoma and T Cells by eIF4A Inhibition

Cancers

Biswendu Biswas, Ramdane Guemiri, Mandy Cadix, Céline M. Labbé, Alina Chakraborty, Martin Dutertre, Caroline Robert, Stéphan Vagner

(2022 24 Feb)

2022

A PD-1/PD-L1 Proximity Assay as a Theranostic Marker for PD-1 Blockade in Patients with Metastatic Melanoma

Clinical Cancer Research

Isabelle Girault, Julien Adam, Shensi Shen, Séverine Roy, Caroline Brard, Sara Faouzi, Emilie Routier, Jéremy Lupu, Sarah Warren, Kristina Sorg, SuFey Ong, Pascale Morel, Jean-Yves Scoazec, Stéphan Vagner, Caroline Robert

(2022 01 Feb)

2021

Non-homologous end-joining at challenged replication forks: an RNA connection?

Trends in Genetics

Charlotte Audoynaud, Stéphan Vagner, Sarah Lambert

(2021 01 Nov)

Actualites

RNA and cancer: the translation process influenced by multiple factors