VALERIE BORDE

Doctor,

Research Director CNRS

Recherche - Paris

Spécialités / domaines

Development, cancer, genetics and epigenetics

Functions within Institut Curie:

Deputy Director of Research Unit

Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) (UMR3244)
Team Leader

Chromosome Dynamics and Recombination
Unit : Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) (UMR3244)

Publications

2022

A POLD3/BLM dependent pathway handles DSBs in transcribed chromatin upon excessive RNA:DNA hybrid accumulation

Nature Communications

S. Cohen, A. Guenolé, I. Lazar, A. Marnef, T. Clouaire, D. V. Vernekar, N. Puget, V. Rocher, C. Arnould, M. Aguirrebengoa, M. Genais, N. Firmin, R. A. Shamanna, R. Mourad, V. A. Bohr, V. Borde, G. Legube

(2022 01 Dec)

2022

The Zip4 protein directly couples meiotic crossover formation to synaptonemal complex assembly

Genes & Development

Alexandra Pyatnitskaya, Jessica Andreani, Raphaël Guérois, Arnaud De Muyt, Valérie Borde

(2022 01 Jan)

2021

Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation

Proceedings of the National Academy of Sciences

Jingqi Dai, Aurore Sanchez, Céline Adam, Lepakshi Ranjha, Giordano Reginato, Pierre Chervy, Carine Tellier-Lebegue, Jessica Andreani, Raphaël Guérois, Virginie Ropars, Marie-Hélène Le Du, Laurent Maloisel, Emmanuelle Martini, Pierre Legrand, Aurélien Thureau, Petr Cejka, Valérie Borde, Jean-Baptiste Charbonnier

(2021 08 Jun)

2021

The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length

Nucleic Acids Research

Dipti Vinayak Vernekar, Giordano Reginato, Céline Adam, Lepakshi Ranjha, Florent Dingli, Marie-Claude Marsolier, Damarys Loew, Raphaël Guérois, Bertrand Llorente, Petr Cejka, Valérie Borde

(2021 07 May)

2021

Methods to Map Meiotic Recombination Proteins in Saccharomyces cerevisiae

Homologous Recombination

Aurore Sanchez, Valérie Borde

(2021 01 Jan)

2020

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Proceedings of the National Academy of Sciences

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

(2020 01 Dec)

2020

Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination

Journal of Biological Chemistry

Md Maminur Rahman, Mohiuddin Mohiuddin, Islam Shamima Keka, Kousei Yamada, Masataka Tsuda, Hiroyuki Sasanuma, Jessica Andreani, Raphael Guerois, Valerie Borde, Jean-Baptiste Charbonnier, Shunichi Takeda

(2020 01 Dec)

2020

Regulation of the MLH1–MLH3 endonuclease in meiosis

Nature

Elda Cannavo, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener, Céline Adam, Ananya Acharya, Nicolas Weyland, Xavier Aran-Guiu, Jean-Baptiste Charbonnier, Eva R. Hoffmann, Valérie Borde, Joao Matos, Petr Cejka

(2020 22 Oct)

2020

Des mécanismes moléculaires aux applications cliniques. L’essentiel du Colloque Réplication-Réparation-Recombinaison 2019

Bulletin du Cancer

Sarah Lambert, Valérie Borde, Jean-Baptiste Charbonnier, Françoise Dantzer, Olivier Espéli, Josée Guirouilh-Barbat, Bertrand Llorente, Gaëlle Legube, Marie-Noëlle Prioleau, Pablo Radicella

(2020 01 Feb)

2020

Coupling DNA Damage and Repair: an Essential Safeguard during Programmed DNA Double-Strand Breaks?

Trends in Cell Biology

Mireille Bétermier, Valérie Borde, Jean-Pierre de Villartay

(2020 01 Feb)