VINCENT LEJOUR

Recherche - Paris

Spécialités / domaines

Molecular biology,

Genetics

Functions within Institut Curie:

Engineer

Genetics of Tumor Suppression
Unit : Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) (UMR3244)

Publications

2023

A systematic approach identifies p53-DREAM pathway target genes associated with blood or brain abnormalities

Disease Models & Mechanisms

2020

Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance

Science Advances

Eléonore Toufektchan, Vincent Lejour, Romane Durand, Neelam Giri, Irena Draskovic, Boris Bardot, Pierre Laplante, Sara Jaber, Blanche P. Alter, José-Arturo Londono-Vallejo, Sharon A. Savage, Franck Toledo

(2020 10 Apr)

2017

Essential role for centromeric factors following p53 loss and oncogenic transformation

Genes & Development

Dan Filipescu, Monica Naughtin, Katrina Podsypanina, Vincent Lejour, Laurence Wilson, Zachary A. Gurard-Levin, Guillermo A. Orsi, Iva Simeonova, Eleonore Toufektchan, Laura D. Attardi, Franck Toledo, Geneviève Almouzni

(2017 01 Mar)

2016

Yeast cells reveal the misfolding and the cellular mislocalisation of the human BRCA1 protein

Journal of Cell Science

Pierre Thouvenot, Lou Fourrière, Elodie Dardillac, Barbara Ben Yamin, Aurianne Lescure, Vincent Lejour, Xavier Heiligenstein, Jean-Baptiste Boulé, Maryse Romao, Graça Raposo-Benedetti, Bernard S. Lopez, Alain Nicolas, Gaël A. Millot

(2016 01 Dec)

2016

p53 downregulates the Fanconi anaemia DNA repair pathway

Nature Communications

Sara Jaber, Eléonore Toufektchan, Vincent Lejour, Boris Bardot, Franck Toledo

(2016 01 Apr)

2015

Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells

Cell Death & Differentiation

A Stedman, S Beck-Cormier, M Le Bouteiller, A Raveux, S Vandormael-Pournin, S Coqueran, V Lejour, L Jarzebowski, F Toledo, S Robine, M Cohen-Tannoudji

(2015 01 Nov)

2015

Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity

Oncogene

B Bardot, R Bouarich-Bourimi, J Leemput, V Lejour, A Hamon, L Plancke, A G Jochemsen, I Simeonova, M Fang, F Toledo

(2015 28 May)

2014

Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival

Oncogene

M Fang, I Simeonova, B Bardot, V Lejour, S Jaber, R Bouarich-Bourimi, A Morin, F Toledo

(2014 06 Mar)

2013

Mutant Mice Lacking the p53 C-Terminal Domain Model Telomere Syndromes

Cell Reports

Iva Simeonova, Sara Jaber, Irena Draskovic, Boris Bardot, Ming Fang, Rachida Bouarich-Bourimi, Vincent Lejour, Laure Charbonnier, Claire Soudais, Jean-Christophe Bourdon, Michel Huerre, Arturo Londono-Vallejo, Franck Toledo

(2013 01 Jun)

2013

Of mice and men

Transcription

Aurélie Morin, Boris Bardot, Iva Simeonova, Vincent Lejour, Rachida Bouarich-Bourimi, Franck Toledo

(2013 01 Mar)