XAVIER LAHAYE

Doctor,

Tenured Research Scientist CNRS

Recherche - Paris

Spécialités / domaines

Research Center,

Immunology,

Virology

Functions within Institut Curie:

Permanent Researcher

Innate immunity
Unit : Immunity and Cancer (U932)

Publications

2021

Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics

Cell Reports

Anvita Bhargava, Alice Williart, Mathieu Maurin, Patricia M. Davidson, Mabel Jouve, Matthieu Piel, Xavier Lahaye, Nicolas Manel

(2021 01 Sep)

2021

Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine

Science Signaling

Marius Döring, Kevin De Azevedo, Guillermo Blanco-Rodriguez, Francesca Nadalin, Takeshi Satoh, Matteo Gentili, Xavier Lahaye, Nilushi S. De Silva, Cécile Conrad, Mabel Jouve, Mireille Centlivre, Yves Lévy, Nicolas Manel

(2021 24 Aug)

2020

Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus

Journal of Extracellular Vesicles

Federico Cocozza, Nathalie Névo, Ester Piovesana, Xavier Lahaye, Julian Buchrieser, Olivier Schwartz, Nicolas Manel, Mercedes Tkach, Clotilde Théry, Lorena Martin‐Jaular

(2020 01 Dec)

2020

A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

Cell Reports

Jarrod S. Johnson, Nicholas De Veaux, Alexander W. Rives, Xavier Lahaye, Sasha Y. Lucas, Brieuc P. Perot, Marine Luka, Victor Garcia-Paredes, Lynn M. Amon, Aaron Watters, Ghaith Abdessalem, Alan Aderem, Nicolas Manel, Dan R. Littman, Richard Bonneau, Mickaël M. Ménager

(2020 01 Jan)

2019

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus

Cell Reports

Matteo Gentili, Xavier Lahaye, Francesca Nadalin, Guilherme P.F. Nader, Emilia Puig Lombardi, Solène Herve, Nilushi S. De Silva, Derek C. Rookhuizen, Elina Zueva, Christel Goudot, Mathieu Maurin, Aurore Bochnakian, Sebastian Amigorena, Matthieu Piel, Daniele Fachinetti, Arturo Londoño-Vallejo, Nicolas Manel

(2019 01 Feb)

2018

NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation

Cell

Xavier Lahaye, Matteo Gentili, Aymeric Silvin, Cécile Conrad, Léa Picard, Mabel Jouve, Elina Zueva, Mathieu Maurin, Francesca Nadalin, Gavin J. Knott, Baoyu Zhao, Fenglei Du, Marlène Rio, Jeanne Amiel, Archa H. Fox, Pingwei Li, Lucie Etienne, Charles S. Bond, Laurence Colleaux, Nicolas Manel

(2018 01 Oct)

2018

Let me in: Control of HIV nuclear entry at the nuclear envelope

Cytokine & Growth Factor Reviews

Anvita Bhargava, Xavier Lahaye, Nicolas Manel

(2018 01 Apr)

2017

Constitutive resistance to viral infection in human CD141 + dendritic cells

Science Immunology

Aymeric Silvin, Chun I Yu, Xavier Lahaye, Francesco Imperatore, Jean-Baptiste Brault, Sylvain Cardinaud, Christian Becker, Wing-Hong Kwan, Cécile Conrad, Mathieu Maurin, Christel Goudot, Santy Marques-Ladeira, Yuanyuan Wang, Virginia Pascual, Esperanza Anguiano, Randy A. Albrecht, Matteo Iannacone, Adolfo García-Sastre, Bruno Goud, Marc Dalod, Arnaud Moris, Miriam Merad, A. Karolina Palucka, Nicolas Manel

(2017 21 Jul)

2016

Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication

Cell Reports

Xavier Lahaye, Takeshi Satoh, Matteo Gentili, Silvia Cerboni, Aymeric Silvin, Cécile Conrad, Abdelhakim Ahmed-Belkacem, Elisa C. Rodriguez, Jean-François Guichou, Nathalie Bosquet, Matthieu Piel, Roger Le Grand, Megan C. King, Jean-Michel Pawlotsky, Nicolas Manel

(2016 01 Apr)

2015

Transmission of innate immune signaling by packaging of cGAMP in viral particles

Science

Matteo Gentili, Joanna Kowal, Mercedes Tkach, Takeshi Satoh, Xavier Lahaye, Cécile Conrad, Marilyn Boyron, Bérangère Lombard, Sylvère Durand, Guido Kroemer, Damarys Loew, Marc Dalod, Clotilde Théry, Nicolas Manel

(2015 11 Sep)