YANN KIEFFER

Recherche - Paris

Spécialités / domaines

Bioinformatics

Functions within Institut Curie:

Research engineer
Stress and cancer
Unité : Cancer, Heterogeneity, Instability and Plasticity - CHIP (U830)

Publications

2021

Dissection of intercellular communication using the transcriptome-based framework ICELLNET

Nature Communications

Floriane Noël, Lucile Massenet-Regad, Irit Carmi-Levy, Antonio Cappuccio, Maximilien Grandclaudon, Coline Trichot, Yann Kieffer, Fatima Mechta-Grigoriou, Vassili Soumelis

(2021 01 Dec)

2021

Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Scientific Reports

Virginie Mieulet, Camille Garnier, Yann Kieffer, Thomas Guilbert, Fariba Nemati, Elisabetta Marangoni, Gilles Renault, Foucauld Chamming’s, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2021 01 Dec)

2021

CD73-Mediated Immunosuppression Is Linked to a Specific Fibroblast Population That Paves the Way for New Therapy in Breast Cancer

Cancers

Ilaria Magagna, Nicolas Gourdin, Yann Kieffer, Monika Licaj, Rana Mhaidly, Pascale Andre, Ariane Morel, Anne Vincent-Salomon, Carine Paturel, Fatima Mechta-Grigoriou

(2021 23 Nov)

2020

A subset of activated fibroblasts is associated with distant relapse in early luminal breast cancer

Breast Cancer Research

Claire Bonneau, Antoine Eliès, Yann Kieffer, Brigitte Bourachot, Sylvain Ladoire, Floriane Pelon, Delphine Hequet, Jean-Marc Guinebretière, Christophe Blanchet, Anne Vincent-Salomon, Roman Rouzier, Fatima Mechta-Grigoriou

(2020 01 Dec)

2020

Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms

Nature Communications

Floriane Pelon, Brigitte Bourachot, Yann Kieffer, Ilaria Magagna, Fanny Mermet-Meillon, Isabelle Bonnet, Ana Costa, Anne-Marie Givel, Youmna Attieh, Jorge Barbazan, Claire Bonneau, Laetitia Fuhrmann, Stéphanie Descroix, Danijela Vignjevic, Pascal Silberzan, Maria Carla Parrini, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2020 01 Dec)

2020

Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer

Cancer Discovery

Yann Kieffer, Hocine R. Hocine, Géraldine Gentric, Floriane Pelon, Charles Bernard, Brigitte Bourachot, Sonia Lameiras, Luca Albergante, Claire Bonneau, Alice Guyard, Karin Tarte, Andrei Zinovyev, Sylvain Baulande, Gerard Zalcman, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2020 01 Sep)

2020

Clinical Interest of Combining Transcriptomic and Genomic Signatures in High-Grade Serous Ovarian Cancer

Frontiers in Genetics

Yann Kieffer, Claire Bonneau, Tatiana Popova, Roman Rouzier, Marc-Henri Stern, Fatima Mechta-Grigoriou

(2020 17 Mar)

2019

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

Cell Metabolism

Géraldine Gentric, Yann Kieffer, Virginie Mieulet, Oumou Goundiam, Claire Bonneau, Fariba Nemati, Ilse Hurbain, Graca Raposo, Tatiana Popova, Marc-Henri Stern, Valérie Lallemand-Breitenbach, Sebastian Müller, Tatiana Cañeque, Raphaël Rodriguez, Anne Vincent-Salomon, Hugues de Thé, Rodrigue Rossignol, Fatima Mechta-Grigoriou

(2019 01 Jan)

2018

miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers

Nature Communications

Anne-Marie Givel, Yann Kieffer, Alix Scholer-Dahirel, Philemon Sirven, Melissa Cardon, Floriane Pelon, Ilaria Magagna, Géraldine Gentric, Ana Costa, Claire Bonneau, Virginie Mieulet, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2018 01 Dec)

2018

Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer

Cancer Cell

Ana Costa, Yann Kieffer, Alix Scholer-Dahirel, Floriane Pelon, Brigitte Bourachot, Melissa Cardon, Philemon Sirven, Ilaria Magagna, Laetitia Fuhrmann, Charles Bernard, Claire Bonneau, Maria Kondratova, Inna Kuperstein, Andrei Zinovyev, Anne-Marie Givel, Maria-Carla Parrini, Vassili Soumelis, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2018 01 Mar)