CurieCoreTech High-content cell-based screening (BioPhenics)

Platform

ELAINE DEL NERY

BioPhenics facility specializes in chemical biology as it relates drug discovery, biological probe discovery and phenotypic characterization of small-molecule effects (siRNAs and chemical compounds) on cellular systems. The facility provides basic and applied research teams with the technical resources and expertise needed to carry out high-content screens.

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Members

ELAINE DEL NERY

Platform manager

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MONALI TAILOR

Engineer assistant

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ELODIE ANTHONY

Engineer

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Key publications

2019

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells
Frontiers in Cell and Developmental Biology

Gaelle Boncompain, Nelly Gareil, Sarah Tessier, Aurianne Lescure, Thouis R. Jones, Oliver Kepp, Guido Kroemer, Elaine Del Nery, Franck Perez
(2019 11 Oct)
2019

Targeting CCR5 trafficking to inhibit HIV-1 infection
Science Advances

Gaelle Boncompain, Floriane Herit, Sarah Tessier, Aurianne Lescure, Elaine Del Nery, Pierre Gestraud, Isabelle Staropoli, Yuko Fukata, Masaki Fukata, Anne Brelot, Florence Niedergang, Franck Perez
(2019 04 Oct)
2019

Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers
Cancer Medicine

Mathilde Vinet, Samyuktha Suresh, Virginie Maire, Clarisse Monchecourt, Fariba Némati, Laetitia Lesage, Fabienne Pierre, Mengliang Ye, Auriane Lescure, Amélie Brisson, Didier Meseure, André Nicolas, Guillem Rigaill, Elisabetta Marangoni, Elaine Del Nery, Sergio Roman‐Roman, Thierry Dubois
(2019 01 May)
2017

Smooth 2D manifold extraction from 3D image stack
Nature Communications

Asm Shihavuddin, Sreetama Basu, Elton Rexhepaj, Felipe Delestro, Nikita Menezes, Séverine M Sigoillot, Elaine Del Nery, Fekrije Selimi, Nathalie Spassky, Auguste Genovesio
(2017 01 Aug)
2016

Screening out irrelevant cell-based models of disease
Nature Reviews Drug Discovery

Peter Horvath, Nathalie Aulner, Marc Bickle, Anthony M. Davies, Elaine Del Nery, Daniel Ebner, Maria C. Montoya, Päivi Östling, Vilja Pietiäinen, Leo S. Price, Spencer L. Shorte, Gerardo Turcatti, Carina von Schantz, Neil O. Carragher
(2016 01 Nov)
2015

Criblage phénotypique à haut contenu pour la chémobiologie et ses enjeux
médecine/sciences

Priscille Brodin, Elaine DelNery, Emmanuelle Soleilhac
(2015 01 Feb)

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