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Team
SEBASTIAN AMIGORENA
Immune responses to cancer

Adaptive immune responses are initiated by the clonal selection of naive T lymphocytes, which recognize their cognate ligands through antigen-specific T cell receptors. T cell receptors are specific for MHC/peptides complexes. These peptides are generated from internalized antigens that are degraded in endocytic compartments.

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News
  • manipulation
    Immune system: spotlight on monocyte fate
    When it detects pathogens such as viruses or bacteria, our immune system triggers certain specific signaling pathways. Institut Curie’s Immune Responses to Cancer team has just identified the signals that determine monocyte differentiation into macrophages or dendritic cells.
    18/11/2021
  • Mnemo Therapeutics
    L’Institut Curie salue la levée de fonds de 75 millions d’euros réalisée par sa spin-off Mnemo Therapeutics
    L’Institut Curie salue la levée de fonds de 75 millions d’euros réalisée par sa spin-off Mnemo Therapeutics co-fondée avec le Memorial Sloan Kettering Cancer Center. Obtenue auprès d’investisseurs européens et américains, il s’agit de la plus grosse levée de fonds jamais effectuée en France par une société de biotechnologies seulement 2 ans après sa création. Fruit de longues années de recherches menées à l’Institut Curie, ces innovations augurent des perspectives prometteuses dans la lutte contre le cancer.
    14/06/2021
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Job offers
  • Technician or Engineer with experience in flow cytometry (M/F)

    The Curie Institute Research Center
    The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.
    The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

  • Postdoctoral Position in Computational Onco-Immunology (M/F)
    The Curie Institute Research Center
    The Institut Curie (http://www.institut-curie.org) is one of the biggest European institutions for cancer research with a strong interdisciplinary tradition. Institut Curie is located in the center of Paris in a rich scientific environment. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.
    The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

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