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Unit
ANA-MARIA LENNON / OLIVIER LANTZ
Immunity and Cancer (U932)

Created in 2005, the INSERM U932 Unit is composed of 10 teams, spread over two buildings (Hôpital Curie and Constant-Burg building, rue Lhomond), with a total of about 120 people.

 

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334
publication since 2017
6
ERC since 2008
3
start-ups
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14 Jun
2023
Institutional seminar "Mayent - Rothschild"
11h-13h
Type I IFNs in health and disease: from trisomy 21 to cancer
Type I interferons (IFNs) activate intracellular antimicrobial programmes and influence the development of innate and adaptive immune responses. We will discuss our results by addressing the biology of IFN in Down syndrome (DS). This syndrome is the consequence of a chromosomal anomaly known as "trisomy 21" in which chromosome 21 is partially or totally tripled. The subunits that make up
14 Jun
2023
Institutional seminar "Mayent - Rothschild"
11h-23h
Lessons from COVID-19 vaccines: high dimensional analyisis of specific T and B cell immune response reveals distinct immunological signatures in 16 combinations of vaccines
The range of vaccines developed against SARS-CoV-2 gave a unique opportunity to study immunization across different platforms. In a single-center cohort with more than 400 volunteers, we analysed the humoral and cellular immune compartments following five COVID-19 vaccines spanning three technologies (adenoviral, mRNA, and inactivated-virus) administered in 16 combinations. Quantification of speci
6 Jun
2023
Seminar Immunology series
11h-23h
Definitional and characterisation of human tissue mononuclear phagocytes and their role in HIV transmission
Mononuclear phagocytes (MNP) consist of Langerhans cells, macrophages and dendritic cells (DC). They can become infected by HIV and transport the virus to its primary target cells (CD4 T cells) in association with their antigen presenting cell function. 

We have revealed that the MNPs within anogenital tissues significantly differ to those in other parts of the body and we have defined thr
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