Unit

Immunity and Cancer (U932)

ANA-MARIA LENNON DUMENIL

Director of Research Unit

OLIVIER LANTZ

Deputy Director of Research Unit

Presentation

Created in 2005, the INSERM U932 Unit is composed of 10 teams, spread over two buildings (Hôpital Curie and Constant-Burg building, rue Lhomond), with a total of about 120 people.

The teams of our department try to better understand the immune responses, and to direct the immune system to better fight against pathogens and/or tumours. Research projects range from fundamental immunology to translationnal immunology and cancer immunotherapy. These approaches include biology, biochemistry and molecular imaging techniques, based on both in vitro and in vivo experimental models, and immunological monitoring, diagnosis, prognosis and immunotherapy studies in cancer patients.

  • Immune responses and cancer (S. AMIGORENA)
  • Myeloid cells and immunity (P. BENAROCH)
  • Integrative analysis of T cell activation (C. HIVROZ)
  • Innate like and CD4+ T cells in cancer (O. LANTZ)
  • Spatio-temporal dynamics of immune cells (A.M. LENNON)
  • Innate immunity (N. MANEL)
  • Translational immunotherapy (E. PIAGGIO)
  • Stem cell immunity (E.POIRIER)
  • Stroma and immunity (H. SALMON)
  • Extracellular vesicles, immune responses and cancer (C. THERY)

Publications

2019Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors

Proceedings of the National Academy of Sciences - 22/10/2019

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Life of the team

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Scientific events

Séminaire Immunology series Immune Surveillance of the Liver

Speakers : Matteo Iannacone,

Du 04/04/2025 00:00 au 04/04/2025 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminairePublishing in Science Immunology: An Inside Look

Speakers : Seth Scanlon

03/02/2025 15:00 - 16:00
Hôpital site de Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire Immunology seriesTranscriptional control of mononuclear phagocytes in homeostasis and disease

Speakers : Bart Lambretch

24/01/2025 11:00 - 23:59
Hôpital site de Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireTreg stability and function in the tumor environment

Speakers : Benoit Salomon

09/12/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireTHE NEUTROPHIL NUCLEUS AS A SIGNALING HUB DURING CHEMOTAXIS AND DNA RELEASE

Speakers : Carole Parent

18/11/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireChromosome and chromatin dynamics at DNA double Strand breaks

Speakers : Gaëlle Legube, ,

05/11/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire Immunology seriesAuto immune mechanisms in Parkinson’s disease

Speakers : Michel Desjardins

28/10/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireWhy immunologists have no other choice but to do conceptual & theoretical immunology

Speakers : Thomas Pradeu

23/09/2024 11:30 - 23:59
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Séminaire Immunology seriesWhen Nuance Matters: The lesser known side of PD1 signaling

Speakers : Enfu Hui

16/09/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire“B cell memory in barrier tissues” - " From the bench to the bedside: cancer immunotherapy with soluble T cell receptors"

Speakers : Mauro Gaya, Mariolina Salio

10/09/2024 14:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Marie Curie
SéminaireFunctional and molecular characterization of cancer-derived extracellular vesicles

Speakers : Dolores Di Vizio

10/06/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireNucleosomes and DNA methylation – implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancers

Speakers : Hironori Funabiki

21/05/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire“Deconstruct-Reconstruct” – Decode cancer-immune crosstalk & probe with organoids

Speakers : Jeroen Roose

13/05/2024 11:00 - 23:59
Hôpital site de Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
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