Structure and Membrane Compartments

Team

MARIA DA GRACA RAPOSO

Structure and Membrane Compartments

In the skin epidermis, pigmented melanocytes contact and communicate with neighboring keratinocytes. Within the melanocyte, the pigment melanin is synthesized and stored in an organelle, the melanosome.

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Members

MARIA DA GRACA RAPOSO

Team Leader

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Post-Doctoral Researcher

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MARIANE SHOUKY

PhD Student

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MARYSE ROMAO

Research engineer

Projects and works

Biogenesis and fate of pigment granules in human skin

Biogenesis and functions of Extracellular vesicles in intercellular communication

Exploiting State of the Art Imaging

Key publications

2020

Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
Nature Communications

Lia Domingues, Ilse Hurbain, Floriane Gilles-Marsens, Julia Sirés-Campos, Nathalie André, Melissa Dewulf, Maryse Romao, Christine Viaris de Lesegno, Anne-Sophie Macé, Cédric Blouin, Christelle Guéré, Katell Vié, Graça Raposo, Christophe Lamaze, Cédric Delevoye
(2020 01 Dec)
2019

Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo
Developmental Cell

Frederik J. Verweij, Celine Revenu, Guillaume Arras, Florent Dingli, Damarys Loew, D. Michiel Pegtel, Gautier Follain, Guillaume Allio, Jacky G. Goetz, Pascale Zimmermann, Philippe Herbomel, Filippo Del Bene, Graça Raposo, Guillaume van Niel
(2019 01 Feb)
2018

Shedding light on the cell biology of extracellular vesicles
Nature Reviews Molecular Cell Biology

Guillaume van Niel, Gisela D'Angelo, Graça Raposo
(2018 01 Apr)
2018

Melanosome Distribution in Keratinocytes in Different Skin Types: Melanosome Clusters Are Not Degradative Organelles
Journal of Investigative Dermatology

Ilse Hurbain, Maryse Romao, Peggy Sextius, Emilie Bourreau, Céline Marchal, Françoise Bernerd, Christine Duval, Graça Raposo
(2018 01 Mar)
2016

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes
Current Biology

Cédric Delevoye, Xavier Heiligenstein, Léa Ripoll, Floriane Gilles-Marsens, Megan K. Dennis, Ricardo A. Linares, Laura Derman, Avanti Gokhale, Etienne Morel, Victor Faundez, Michael S. Marks, Graça Raposo
(2016 01 Jan)