Directory of Doctors and Researchers

ADELINE LABLANCHE

Ingénieur de recherche
Recherche - Paris
Spécialités / domaines
Biology,
Molecular biology,
Cancer,
Research Center,
Epigenetics,
Translational research,
Single Cell
Functions within Institut Curie:
Présentation

I am working in Céline VALLOT's since 2017, and I am developping technologies and methods to study epigenome in triple negative breast cancer (TNBC), mainly looking at H3K27me3, HK4me1 and H3K27ac histones modifications. First, we developped bulk methods (ChIPseq), and we are now moving towards single-cell technolgies (single-cell ChIPseq, single-nulcei CUT&Tag), to appreciate epigenomic heterogeneity in our samples.

Publications
H3K27me3 conditions chemotolerance in triple-negative breast cancer
Nature Genetics
Justine Marsolier, Pacôme Prompsy, Adeline Durand, Anne-Marie Lyne, Camille Landragin, Amandine Trouchet, Sabrina Tenreira Bento, Almut Eisele, Sophie Foulon, Léa Baudre, Kevin Grosselin, Mylène Bohec, Sylvain Baulande, Ahmed Dahmani, Laura Sourd, Eric Letouzé, Anne-Vincent Salomon, Elisabetta Marangoni, Leïla Perié, Céline Vallot
Prognostic factors of metastatic neuroendocrine carcinoma under first-line treatment with platinum etoposide with a focus on NEC score and Rb expression: Results from the multicentre RBNEC study of the Groupe d’Etude des Tumeurs Endocrines (GTE) and the E
European Journal of Cancer
Julien Hadoux, Christina Kanaan, Alice Durand, Ségolène Hescot, Vincent Hautefeuille, Guillaume Cadiot, Igor Tauveron, Sandrine Laboureau, Christine Do Cao, Thomas Walter, Caroline Petorin, Odile Blanchet, Arnaud Jannin, Céline Gu, Matthieu Faron, Emmanuelle Leteurtre, Marie-Christine Rousselet, Juliette J. Zakeyh, Aude Marchal, Denis Chatelain, Clément Beaulaton, Valérie Hervieu, Michel Ducreux, Jean-Yves Scoazec, Eric Baudin
H3K27me3 is a determinant of chemotolerance in triple-negative breast cancer
bioRxiv
Justine Marsolier, Pacôme Prompsy, Adeline Durand, Anne-Marie Lyne, Camille Landragin, Amandine Trouchet, Sabrina Tenreira Bento, Almut Eisele, Sophie Foulon, Léa Baudre, Kevin Grosselin, Mylène Bohec, Sylvain Baulande, Ahmed Dahmani, Laura Sourd, Eric Letouzé, Elisabetta Marangoni, Leïla Perié, Céline Vallot
CD44 regulates epigenetic plasticity by mediating iron endocytosis
Nature Chemistry
Sebastian Müller, Fabien Sindikubwabo, Tatiana Cañeque, Anne Lafon, Antoine Versini, Bérangère Lombard, Damarys Loew, Ting-Di Wu, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Adeline Durand, Céline Vallot, Sylvain Baulande, Nicolas Servant, Raphaël Rodriguez
X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene
Journal of Allergy and Clinical Immunology
Chantal Lagresle-Peyrou, Sonia Luce, Farid Ouchani, Tayebeh Shabi Soheili, Hanem Sadek, Myriam Chouteau, Amandine Durand, Isabelle Pic, Jacek Majewski, Chantal Brouzes, Nathalie Lambert, Armelle Bohineust, Els Verhoeyen, François-Loïc Cosset, Aude Magerus-Chatinet, Frédéric Rieux-Laucat, Virginie Gandemer, Delphine Monnier, Catherine Heijmans, Marielle van Gijn, Virgil A. Dalm, Nizar Mahlaoui, Jean-Louis Stephan, Capucine Picard, Anne Durandy, Sven Kracker, Claire Hivroz, Nada Jabado, Geneviève de Saint Basile, Alain Fischer, Marina Cavazzana, Isabelle André-Schmutz
Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth
Nature Cell Biology
Jonathan Lévy, Wulfran Cacheux, Medhi Ait Bara, Antoine L’Hermitte, Patricia Lepage, Marie Fraudeau, Coralie Trentesaux, Julie Lemarchand, Aurélie Durand, Anne-Marie Crain, Carmen Marchiol, Gilles Renault, Florent Dumont, Franck Letourneur, Myriam Delacre, Alain Schmitt, Benoit Terris, Christine Perret, Mathias Chamaillard, Jean-Pierre Couty, Béatrice Romagnolo
Directory of Doctors and Researchers