DAVID GENTIEN

Ingénieur de recherche
Recherche - Paris
Spécialités / domaines
Genomics,
Translational research
Functions within Institut Curie:
Présentation

David Gentien has been in charge of the Genomics Platform since 2008 within the Translational Research Department.

Thanks to an open and dynamic team, the platform facilitates the implementation of genomic analyses according to the needs of researchers, biologists and clinicians from various backgrounds. To do this, the platform ensures that the most appropriate approaches are applied to the requests, and that the most exhaustive and controlled results are delivered in the shortest possible time. Depending on the project, we carry out the first steps of data analysis but our limits currently stop where the expertise of bioinformaticians begins, for example for exploratory analyses.

Operating as a service platform, the platform works daily in a collaborative mode with local and international teams from a wide range of fields including basic, translational, clinical, pharmaceutical and biotechs. If you have specific needs that require special attention, then contact us! We love to take on challenges and push the current limits of genomics!

Since it is highly translational, the genomics platform also participates in diagnostic assistance analyses for molecular medicine, and works in the field of predictive medicine in close collaboration with the Institut Curie hospital's genetics department.

Finally, in order to remain young even over the years, we strive to welcome trainees according to our current capacities and the need for innovation.

Publications
Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer
The Journal of Pathology
Nanor Sirab, Damien Drubay, Pascale Maillé, Tatiana Popova, Carine Ngo, David Gentien, Anissa Moktefi, Pascale Soyeux‐Porte, Romain Pelletier, Cécile Reyes, Emilie Henry, Damien Pouessel, Dimitri Vordos, Thierry Lebret, Aurélien Reyniès, Xavier Paoletti, François Radvanyi, Yves Allory
A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial
npj Precision Oncology
Istvan Petak, Maud Kamal, Anna Dirner, Ivan Bieche, Robert Doczi, Odette Mariani, Peter Filotas, Anne Salomon, Barbara Vodicska, Vincent Servois, Edit Varkondi, David Gentien, Dora Tihanyi, Patricia Tresca, Dora Lakatos, Nicolas Servant, Julia Deri, Pauline du Rusquec, Csilla Hegedus, Diana Bello Roufai, Richard Schwab, Celia Dupain, Istvan T. Valyi-Nagy, Christophe Le Tourneau
A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression
Nature Communications
Jing Liu, Daniela Ottaviani, Meriem Sefta, Céline Desbrousses, Elodie Chapeaublanc, Rosario Aschero, Nanor Sirab, Fabiana Lubieniecki, Gabriela Lamas, Laurie Tonon, Catherine Dehainault, Clément Hua, Paul Fréneaux, Sacha Reichman, Narjesse Karboul, Anne Biton, Liliana Mirabal-Ortega, Magalie Larcher, Céline Brulard, Sandrine Arrufat, André Nicolas, Nabila Elarouci, Tatiana Popova, Fariba Némati, Didier Decaudin, David Gentien, Sylvain Baulande, Odette Mariani, Florent Dufour, Sylvain Guibert, Céline Vallot, Livia Lumbroso-Le Rouic, Alexandre Matet, Laurence Desjardins, Guillem Pascual-Pasto, Mariona Suñol, Jaume Catala-Mora, Genoveva Correa Llano, Jérôme Couturier, Emmanuel Barillot, Paula Schaiquevich, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Lisa Golmard, Claude Houdayer, Hervé Brisse, Isabelle Bernard-Pierrot, Eric Letouzé, Alain Viari, Simon Saule, Xavier Sastre-Garau, François Doz, Angel M. Carcaboso, Nathalie Cassoux, Celio Pouponnot, Olivier Goureau, Guillermo Chantada, Aurélien de Reyniès, Isabelle Aerts, François Radvanyi
Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer
Clinical Cancer Research
Laetitia Marisa, Yuna Blum, Julien Taieb, Mira Ayadi, Camilla Pilati, Karine Le Malicot, Côme Lepage, Ramon Salazar, Daniela Aust, Alex Duval, Hélène Blons, Valérie Taly, David Gentien, Audrey Rapinat, Janick Selves, Sophie Mouillet-Richard, Valérie Boige, Jean-François Emile, Aurélien de Reyniès, Pierre Laurent-Puig
Reference standards for gene fusion molecular assays on cytological samples: an international validation study
Journal of Clinical Pathology
Umberto Malapelle, Francesco Pepe, Pasquale Pisapia, Annalisa Altimari, Claudio Bellevicine, Hans Brunnström, Rossella Bruno, Reinhard Büttner, Luis Cirnes, Carlos E De Andrea, Dario de Biase, Catherine I Dumur, Kajsa Ericson Lindquist, Gabriella Fontanini, Eugenio Gautiero, David Gentien, Paul Hofman, Veronique Hofman, Antonino Iaccarino, Maria Dolores Lozano, Clara Mayo-de-Las-Casas, Sabine Merkelbach-Bruse, Fabio Pagni, Ruth Roman, Fernando C Schmitt, Janna Siemanowski, Sinchita Roy-Chowdhuri, Giovanni Tallini, Francesc Tresserra, Sara Vander Borght, Philippe Vielh, Elena Vigliar, Giulia Anna Carmen Vita, Birgit Weynand, Rafael Rosell, Miguel Angel Molina Vila, Giancarlo Troncone