Team
DNA Recombination, Replication and Genome Stability
Thematic areas of research:
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Team
SARAH LAMBERT
DNA Recombination, Replication and Genome Stability
During an average human life span, each individual copies several light-years of DNA to ensure organism development and tissue homeostasis. Flaws in the DNA replication process, known as replication stress, result in inaccurate chromosome duplication and subsequent mitotic abnormalities.
Members
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Past members
ANISSIA AIT-SAADA
PhD Student
CHARLOTTE AUDOYNAUD
PhD Student
VIRGINIE BOUCHERIT
Engineer
DINGLI DAI
PhD Student
LOUISE DUPOIRON
Engineer assistant
JULIEN HARDY
Post-Doctoral Researcher
MY-ANNE HONG
Engineer
KAROL KRAMARZ
Post-Doctoral Researcher
ANA CAROLINA TEIXEIRA DA SILVA
PhD Student
Key publications
All publications
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Recombination-dependent replication: new perspectives from site-specific fork barriersCurrent Opinion in Genetics & Development
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News
All news
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New major players in the protection of DNA replication forks are identified
In an article published on March 2, 2023, in the journal Molecular Cell, the team led by Sarah Lambert, in collaboration with researchers from the Institute for Integrative Biology of the Cell, revealed a mechanism that ensures the integrity of DNA replication forks. Based on the combination of RNA and the end-joining factor Ku, it represents a potential new therapeutic target to fight cancerous cells.13/03/2023
