Team
Signaling and cancer progression
Thematic areas of research:
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Team
ALAIN EYCHENE
Signaling and cancer progression
Our team has a long-lasting expertise in the signaling field in cancer by working for several decades on two oncogenic families: the RAF Ser/Thr kinases (Peyssonnaux and Eychene, Biol Cell 2001) and the MAF transcription factors (Eychene et al., Nat Rev Cancer 2008).
Members
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Photos d'équipe
Key publications
All publications
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AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric ModelsClinical Cancer Research
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An autocrine ActivinB mechanism drives TGF β/Activin signaling in Group 3 medulloblastomaEMBO Molecular Medicine
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SHH medulloblastoma in a young adult with a TCF4 germline pathogenic variationActa Neuropathologica
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NRAS-driven melanoma: A RAF can hide anotherMolecular & Cellular Oncology
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Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like FaciesThe American Journal of Human Genetics
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PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysisNature Communications
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The survival gene MED4 explains low penetrance retinoblastoma in patients with large RB1 deletionHuman Molecular Genetics
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A new MAFia in cancerNature Reviews Cancer