Unit
Genetics and Developmental Biology (UMR3215 / U934)
Thematic areas of research:
Image
To top
Unit
PIERRE LEOPOLD / YOHANNS BELLAICHE
Genetics and Developmental Biology (UMR3215 / U934)
The research Unit “Genetics and Developmental Biology” of Institut Curie is composed of nine teams addressing fundamental questions related to the development of organisms and its pathological dysfunctions.
Teams
Key figures
16
publications in 2020
3
ongoing ERC in 2020
24
PhD Students in 2020
Key publications
All publications
-
Brain adiponectin signaling controls peripheral insulin response in DrosophilaNature Communications
-
-
-
-
-
News
All news
-
Drs. Allison Bardin and Valérie Borde elected members of the European EMBO organizationTo mark its 60th anniversary, the European Molecular Biology Organization (EMBO) has unveiled its 100 new members. Among them are nine French researchers, including Drs. Allison Bardin and Valérie Borde, team leaders at Institut Curie Research Center. Their mission: to promote the life sciences, guide strategic research choices and encourage the emergence of a new generation of excellent researchers.09/07/2024 -
Dr. Phong Nguyen a new junior team leader in Paris, explores cardiac regenerationDr. Phong Nguyen recently arrived at Institut Curie Research Center and just created a new team in the Genetics and Developmental Biology Unit (CNRS UMR3215 / Inserm U934 / Sorbonne University) in Paris. This team focuses on the processes that enable the heart to heal following an injury, based on the cardiac regeneration model observed in zebrafish.20/06/2024 -
Cell contraction drive the initial shaping of human embryosHuman embryo compaction, an essential step in the first days of an embryo’s development, is driven by the contractility of its cells. This is the finding of a team of scientists from CNRS, Institut Curie, Inserm, AP-HP and the Collège de France.02/05/2024 -
Congratulations to Dr. Jean-Léon Maître, recipient of the Richard Lounsbery AwardDr. Jean-Léon Maître, head of the Mechanics of Mammalian Development team, has been honored with the prestigious Richard Lounsbery Award by the French Academy of Sciences and the American National Academy of Sciences (NAS). The award recognizes the research carried out by his team to understand the mechanisms underlying the construction of the mammalian embryo.15/03/2024 -
Embryo fragmentation under the microscopeDuring the early days of its existence, cells of human embryos may fragment. This phenomenon is common and affects the embryo’s survival. In a study published in EMBO Journal, researchers from CNRS and Institut Curie used a “light-sheet” microscope to discover that cell fragmentation is caused, in mouse models, by contractions on the surface of the embryo and occur when signals persist abnormally from when the maternal oocyte is formed.22/08/2023 -
Congratulations to Déborah Bourc’his, winner of an ERC Advanced GrantOn Thursday March 30, 2023, Déborah Bourc’his, team leader at Institut Curie’s Research Center, was awarded one of the European Research Council’s prestigious ERC Advanced Grants for her promising work on interactions between transposons and male reproductive cells.05/04/2023
Scientific events
All scientific events
3 Jul
2024
Seminar
11h-23h
Building a Multimodal Atlas of Vertebrate Development
Elucidating the developmental processes of organisms requires a comprehensive understanding of cell lineages across spatial, temporal, and molecular dimensions. Advances in imaging and omics technologies allow us to generate technically challenging multidimensional datasets that capture developmental dynamics at unprecedented resolution and across scales (from molecule to organism). In this talk,
6 Jun
2024
Institutional seminar "Mayent - Rothschild"
10h-23h
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTION
In the Drosophila optic lobes, ~200 types of neurons organized as 800 columns process the inputs from 800 unit-eyes. We study how this variety of neurons is generated during development and how connectivity among these neurons is regulated
The ~800 Neural stem cells in the medulla sequentially express a series of temporal transc
The ~800 Neural stem cells in the medulla sequentially express a series of temporal transc
30 May
2024
Institutional seminar
10h-23h
Coping with mechanical stress: tissue dynamics during development, homeostasis and repair.
Abstract:
During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how mechanical forces can influen
Abstract:
During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how mechanical forces can influen
2 May
2024
Institutional seminar "Mayent - Rothschild"
11h-23h
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTION
Claude Desplan1,2, Nikos Konstantinides1, Felix Simon1, Neset Ozel1, Isabel Holguera1, Jennifer Malin1, Yen Chen1, and Bogdan Sieriebriennikov1
1 Center for Developmental Genetics, Department of Biology, New York University, New York, USA; 2 Center for Genomics and System Biology, NYU Abu Dhabi, UAE.
In th
1 Center for Developmental Genetics, Department of Biology, New York University, New York, USA; 2 Center for Genomics and System Biology, NYU Abu Dhabi, UAE.
In th
2 May
2024
Institutional seminar
10h-23h
Common threads in regeneration: mechano-chemical insights from a jellyfish model
How randomly injured animals can appropriately re-establish positional information and control the deployment of repair programs are key questions of regenerative biology. The hydrozoan jellyfish Clytia hemisphaerica has recently emerged as an original model organism for probing repair phenomena, thanks to its remarkable regenerative abilities. Coping with frequent injuries in the planktonic envir