The Mechanics and Genetics of Embryonic and Tumour Development team studies the role of mechanical strain and deformation of macroscopic biological structures at the cell or multi-cellular scale, into the regulation and the generation of active biochemical processes at the microscopic molecular scale, including gene expression, in vivo. The group focuses on the coupling between mechanical strains and biochemical signalling in developmental and cancer biology.
Cancer under pressureA team of Institut Curie researchers has conducted in-depth exploration of the mechanisms linking mechanical pressure and carcinogenesis. They discovered a key protein, a potential therapeutic target against a number of cancers. This work has been published in the journal Communications Biology.31/03/2022