The Mechanics and Genetics of Embryonic and Tumour Development team studies the role of mechanical strain and deformation of macroscopic biological structures at the cell or multi-cellular scale, into the regulation and the generation of active biochemical processes at the microscopic molecular scale, including gene expression, in vivo. The group focuses on the coupling between mechanical strains and biochemical signalling in developmental and cancer biology.
Cancer under pressureA team of Institut Curie researchers has conducted in-depth exploration of the mechanisms linking mechanical pressure and carcinogenesis. They discovered a key protein, a potential therapeutic target against a number of cancers. This work has been published in the journal Communications Biology.31/03/2022
The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a of more than 1000 employees with a strong international representativeness.
The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.
Located in the center of Paris, the Research Center is an internationally renowned research institution bringing together physicists, biologists, clinicians, chemists, and bioinformaticians.