Unit
Nuclear dynamics (UMR3664)
Thematic areas of research:
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Unit
ANGELA TADDEI / NATHALIE DOSTATNI
Nuclear dynamics (UMR3664)
Teams in this unit investigate the mechanisms underlying the stability and the plasticity of genetic and epigenetic information in normal or pathological contexts such as cancer. Using complementarity approaches, we develop an integrated view of the functional organization of the genome at different scales: from the molecule to the cell to the organism.
Teams
Key figures
18
nationalities for 55 people
6
model systems
37200
billion nuclei in the human body
Key publications
All publications
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CENP-A overexpression promotes distinct fates in human cells, depending on p53 statusCommunications Biology
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3 minutes to precisely measure morphogen concentrationPLOS Genetics
News
All news
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A Key Protein for DNA Repair Observed in YeastFor the first time, researchers from Institute Curie, led by Dr. Angela Taddei, have highlighted one of the cellular mechanisms that come into play during DNA repair.21/08/2023 -
Institut Curie - Institut Pasteur partnership: two joint projects to promote innovation and advancement of knowledgeImplementing their collaborative research strategy, Institut Curie and Institut Pasteur have raised the impressive amount of €600,000 to finance two research projects involving two teams from each organization. The MUCTOLIN project, looking at the role of tolerance induced by mucus during Listeria infection, and the TicTac project, which aims to study the effects of geometry on the healthy or cancerous status of a cell or on its development, were chosen.28/04/2023 -
Congratulations to Leïla Périé and Antoine Coulon, winners of the CNRS Bronze Medal 2023Two scientists from the Research Center have just been honored by the CNRS. Each year the organization rewards the women and men who have made the greatest contributions to its reputation and progress in research. The 2023 edition once again recognizes the excellence of the researchers working at Institut Curie’s Research Center.04/04/2023 -
Manipulating chromosomes in living cells reveals that they are fluidFor the first time, scientists from CNRS, Institut Curie and Sorbonne Université have been able to act physically on chromosomes in living cells. By subjecting the chromosomes to different forces using magnets, they discovered that chromosomes are in fact very fluid – almost liquid – outside cell division phases. This study is published in Science on July 29, 2022.01/08/2022
Scientific events
All scientific events
12 Dec
2024
Webinar
13h-15h
Prévention des Violences Sexistes et Sexuelles
Objectifs pédagogiques de la formation
- Connaître les définitions légales des violences sexistes et sexuelles
- Connaître les principales données chiffrées sur le sujet
- Comprendre les conséquences des violences sexistes et sexuelles
- Connaître les responsabilités et obligations de l’employeur, les sanctions encourue
- Connaître les définitions légales des violences sexistes et sexuelles
- Connaître les principales données chiffrées sur le sujet
- Comprendre les conséquences des violences sexistes et sexuelles
- Connaître les responsabilités et obligations de l’employeur, les sanctions encourue
14 Nov
2024
Webinar
13h-15h
Sexist and Sexual Violence Prevention
Training objectives
- Understand the legal definitions of sexist and sexual violence
- Understand the main figures on the subject
- Understand the consequences of gender-based and sexual violence
- Understand the employer's responsibilities and obligations, as well as sanctions and procedures.
- Know how to listen and provide guidance
To join the seminar : https://shorturl.at/awJU0
- Understand the legal definitions of sexist and sexual violence
- Understand the main figures on the subject
- Understand the consequences of gender-based and sexual violence
- Understand the employer's responsibilities and obligations, as well as sanctions and procedures.
- Know how to listen and provide guidance
To join the seminar : https://shorturl.at/awJU0
10 Oct
2024
Webinar
13h-15h
Prévention des Violences Sexistes et Sexuelles
Objectifs pédagogiques de la formation
- Connaître les définitions légales des violences sexistes et sexuelles
- Connaître les principales données chiffrées sur le sujet
- Comprendre les conséquences des violences sexistes et sexuelles
- Connaître les responsabilités et obligations de l’employeur, les sanctions encourue
- Connaître les définitions légales des violences sexistes et sexuelles
- Connaître les principales données chiffrées sur le sujet
- Comprendre les conséquences des violences sexistes et sexuelles
- Connaître les responsabilités et obligations de l’employeur, les sanctions encourue
1 Oct
2024
Seminar Nuclear dynamic series
09h-10h
Shaping the genome with SMC motors
How are the meters of DNA inside our cells organised in 3D to allow key chromosomal processes to take place in the correct manner? Key to this organisation are the SMC motors cohesin and condensin. But how do these molecular machines actually do what they do? And how are they regulated such that they can control the vast array of chromosomal processes ranging from transcription to chromosome segre
26 Sep
2024
Seminar
09h-10h
Morphology meets Genomics Evolution of development in flies , beetles and spiders
Understanding the evolutionary forces shaping the breathtaking morphological diversity present in nature is one prerequisite to describe and maintain this biodiversity. Linking genetic variation to phenotypic differences is a crucial step towards this goal because information about the appearance of an organism is stored in its genome. New sequencing technologies fueled exciting advances in the id